TriG/HDL-C ratio and cardiovascular risk

How relevant is TriG/HDL-C ratio and if its value above 2 suggests higher risk in an individual?

The ratio is a marker of insulin resistance, and does portend a higher risk of heart disease. One meta-analysis, identified a “cut off” of 2.8 for men and 2.5 in women. All that being said, the ratio is not used very often by us in clinical practice. I continue to recommend people focus on LDL cholesterol as an absolute number as the single most important marker since evidence-based recommendations are clear cut on what do regarding LDL and heart disease.

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