Protein intake and kidney function
Dr. Joshi, could you please advise whether there are any studies showing that protein intake increases serum creatinine or adversely affects kidney function? My source of protean is from plant based protein powder called Organic Truvani, mung daal/lentils, almonds, tempeh, and egg white.
Thanks for asking—clear answer: in people with healthy kidneys, higher protein intake does not damage kidneys. It can raise serum creatinine a little, but that’s usually from greater creatine/creatinine generation with more muscle/protein, not true kidney injury. Large trials and meta-analyses show no decline in eGFR or rise in albuminuria with higher protein in healthy adults; in chronic kidney disease (CKD), however, very high protein can accelerate decline, so targets are lower. Practical points for your pattern: plant-forward proteins (mung dal/lentils, tempeh), egg whites, and a reputable plant protein powder are kidney-friendly. If you lift or increase protein, expect creatinine to bump slightly; cystatin C is a better kidney marker in that setting. If you ever have diabetes, hypertension, or known CKD, keep protein moderate and monitor eGFR and urine albumin.