High-dose vitamin toxicity

Can high-dose vitamin supplements cause health problems even though they're "natural"?

Yes. Being natural doesn't mean a supplement is safe. High doses of fat-soluble vitamins (A, D, E, K) can cause toxicity syndromes. In one case, high-dose Vitamin D contributed to worsening sleep issues, and low-dose hydrocortisone (taken as a supplement) contributed to fluid retention.

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